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Steroids/Terpenoids: 2 g nano herbal andaliman were macerated with 40 ml ether for 2 hours. The saponin is positive if there is foam in not less than 10 minutes as high as 1-10 cm after adding 2 drops of hydrochloric acid 2 N foam was not lost. Saponin: 1 g of nano herbal andaliman and 20 ml of hot water have been shaken for 20 seconds. After cooling, 10 ml of kerosene ether is added and then shaken and let stand until separation, the methanol layer is taken and then evaporated at 40☌, the remainder is dissolved in ethyl acetate and filtered by filtrate to be tested with 0.5 g zinc powder and 0.1 g powder magnesium. įlavonoids: 1 g of nano herbal andaliman mixed in 20 ml of methanol then reflux 10 minutes. The filtrate that has been filtered in the juice with 20 ml mixture of chloroform and isopropanol (3: 2) to be tested against sugar compounds and non-sugar compounds.
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After chilling 20 ml of filtrate added 10 ml of distilled water and 10 ml of lead (II) acetate 0.4 M were shaken and left for 5 minutes. Glycosides: 3 g of nano herbal andaliman extracted in 30 ml mixture of 7 parts ethanol 96% and 3 parts of distilled water, then added concentrated sulfuric acid and refluxed in 10 minutes.
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Positive alkaloids if sediment or turbidity occurs.
FARMAKOPE INDONESIA EDISI 4 PDF TRIAL
The trial was conducted with Meyer reagent. The impact of the combination of these two herbs needs to be seen in the liver in terms of their safety effects in preeclamptic patientsĪlkaloids: 1 g of nano herbal andaliman was put in a test tube then added 18 ml of distilled water and 2 ml of 2 N hydrochloric acids then heated for 2 minutes. The liver is the largest organ in the body that plays a role in detoxifying poisons in the blood, breaking down or changing the nature of toxic substances so that it can be released through urine. Changes in drug molecules into nanometer scales provide a significant change in physicochemical properties and can improve the efficacy of these drug molecules. Constraints that often occur in herbal medicines are difficult active substances to penetrate the lipid membrane of body cells because they have a large molecular size and low solubility in water that causes poor absorption and bioavailability. Nanotechnology is a system that has several advantages, namely being able to modify the characteristics of the surface, small size, high loading capacity so that it can be given in high concentrations. Extra Virgin Olive Oil (EVOO) from Olive fruit contains antioxidants, namely Vitamin E, hydroxityrosol and tyrosol. The content of this plant is thought to have activities to reduce PE because andaliman fruit has also been reported to have anti-inflammatory activity and antioxidant activity. Andaliman extract contains chemicals in the form of alkaloids, steroids and terpenoids, which have antioxidant activity and antimicrobial, repellent and kill insects. This plant has been used as a contraceptive for generations as an anti-fertility. Īndaliman ( Zanthoxylum acanthopodium.) is a spice that is used for traditional Batak cuisine, Norther Sumatera, Indonesia. The international non-governmental organisation forum on Indonesian Development stated that Indonesia is a country in Southeast Asia with the highest maternal mortality rate of 359/100.000 births. According to the Indonesian Demographic and Health Survey in 2007, PE contributed up to 24% of maternal deaths in Indonesia and made it the second leading cause of maternal mortality in Indonesia. PE is a life-threatening disease for mother and fetus in Indonesia. Recent data show that the contribution of preeclampsia is estimated to be about 5 times that of morbidity & maternal-newborn mortality. Preeclampsia (PE) is a multi-system disorder that is a major cause of maternal morbidity and mortality worldwide.